So long as your setup is good, no. Anecdotal intertubes evidence suggests drops are rare with the narrow/wide rings, but that they can happen.
For retention, sure, the rings are all working great when everything is new. But what about when everything gets a bit worn? Not enough to need replacement, but loose enough to allow chaindrop?
These are spendy chainrings - I don't want to destroy it and have to buy a new one, and don't want to destroy it and have to end a ride because if doing so.

I've got them on two bikes now, both still running variants of the MRP AM-Guide. Gives me bash protection, and upper retention - paired with the clutch rear mechs, everything has been peachy so far.
They add minimal weight, and with only an upper guide bit they don't add any friction to the system. Win-win.