Are you 100 kg + and in good shape or carrying a bit of a "energy reserve" on the belly And how much does your bike/gear weigh?

I use my Troll (26" wheels x 2" tires) with a 42-16 ratio with 175 mm crank arms. I am 158 lbs, max 75 lbs bike/gear weight and in decent shape.

Touring, I find generally I run out of gears on the top end while on flat ground cruising, but like having the low gearing for the hills. Off tour, I run out of gears in about 3 seconds. Not suitable at all. When my sprockets wear out in about another 5000 km or so, I'm going to use a 44 or 46 instead, along with about 10 lbs less gear.