Sooo...what's the budget?
I ask because you're big enough that anything off-the-shelf will be hard to fit, and things like stem length and saddle setback do some very odd things to bike handling.
I don't subscribe to the school that says you should go for slow handling for a first road bike. Depends what kind of guy you are. I wanted my first car to handle really well even though I was a new driver.
At your size, look at Somas as well. There is a model with a double TT you can get in a 64, I believe.
But, if you have the budget, I'd go for the KHS or full custom. I have a neighbor who has a Zinn. It's very nice, and, since he's a tiny 6'5, he let me try it. Rode very nicely. Zinn makes the KHS. Stable, but plenty quick.
If you can afford custom, you could easily get a Gunnar relatively cheaply, and it would fit. Or you can go nuts and get something even more special. Off the top of my head, I've seen some very big Sevens that looked very nice.
Finally, as a first step, get a professional fit. That will give you a ball park to target in terms of length of top tube. It'll help you figure out whether a 63 or a 64 is big enough.