I know setback is a big variable. By moving my saddle back ~1" from center, my height changed by about 1/2" from where my sit bones sit, but not the height from the BB center to the top of the saddle directly above the seat tube.

Anyway, in my case, I run with my saddle setback quite a bit because my femur length is around 24.5" when measured against the wall to kneecap at 90deg.

This is why my thought are moving in the direction of needing to lower my saddle, because I sit back so far on the saddle, so my saddle height is effectively increased when doing so. Because of my long femurs, I use alot of glute muscle and quads (even hamstrings) when seated. When standing and climbing short hills, that's when I really feel the calves kick in.