All those holes are there for a purpose. Find a 48h rim and use them Make sure the rims and spokes are neon colored, too.

But on a 36 hole rim, you could use 6 groups of 3 spokes per side, skipping every 4th hole (6*3 =18, 6*4=24)
or on a 32 hole rim, 8 pairs, skipping every 3rd hole (8*2=16, 8*3=24).
I guess to choose the best look you'd need to decide on #crosses .