How long are your rides and what kind of seat do you have now?
I've done my usual commute of 16.5 miles in cotton underwear
and pants. I'ts doable but my preference is using padded shorts
or tights. Now for 100 miles rides; I'm wearing bike specific bottoms
for sure. Some folks swear by Brooks saddle and other similar type
seats; Selle Anatomica, etc. Saying that they are so comfy; you can
wear anything that you prefer.