Are you camping, or riding from hotel to hotel?
If the former, carrying the necessary gear on the bike may be a challenge. Definitely load the bike up with all that gear and do a test run, meaning go ride 20 miles and see what it is like. A loaded bike rides differently than an unloaded one, and a heavily loaded bike different yet. "Different" not meaning better, usually.
Are you in shape for riding 30 or 50 miles a day, whatever it will be? Depending on how much you have been riding lately, you might want or need to train up a bit.
Any chance of being caught out after dark? Then you need lights - not optional.
What are the roads like? Narrow two lane, busy four lane, with or without bike lane or wide shoulder? How much auto/truck traffic, how much bike traffic, are you comfortable riding on those sorts of roads? Need to know that - you might even consider driving your proposed route first.
jyl,
I'm not sure what I am going to be doing yet. I would love to camp it (just to say that, at least once I bicycle camped, because this is my first time touring, I am just testing it out to see if it is something that I would like to continue with), but I am not sure of my logistics yet. Fo rlights, I've got my Reelights, as well as my Knog Blinder 200, and will most likely be investing a couple more, because let's face it, bike stuff is addicting!