Originally Posted by Campag4life

My suggestion is experiment with saddle setback and handlebar height. Oddly, more setback and greater distance to the handlebar and a slightly lower handlebar is many times the recipe for low hand pressure. This is very counterintuitive and goes right over the head of many amateur cyclists who ride cramped with a closer in handlebar with little saddle setback and the arms are in compression. If you move your weight more rearward and balance your body on the saddle better and move the bar away this will will take weight off your hands. Again, the opposite of what many do.
HTH.