I have no direct experience with current Ti touring bikes. But I have been happily touring on and off pavement on a Ti Bruce Gordon RNR for the last 25 years. An ovalized and over-sized down tube manages touring loads well. Tire size is limited to 700x47 but worked well on the Divide Ride except for deepest sand.

A friend rode my bike about ten years ago and then had Seven Cycles replicate it in Ti. He rode the Trans Am and then Prudhoe Bay, Alaska to Panama in rapid succession. He has been very pleased with the bike.