Carrying the bike up stairs or lifting it onto a bus rack, it actually is the overall weight that matters.
At 57 and with a bit of middle age around my middle, I'm not a strapping young lad. Although I will confess to the male part.
I live on the third floor, and the bikes stay in the apartment with me. Two of the three have Shimano Alfine DH-S501 dyno hubs. It's not a problem carrying them up and down the stairs.
Since this is the commuting forum, you'll also understand when I say, that the hub weighs less than my panniers and their contents, which I don't take off to make a second trip up the stairs. It probably weighs less than my pump, seat bag and its contents too.
Actually, the hub weighs less than the two MagicShine batteries it replaced. I never took those off either to carry the bike up the stairs.
I do, however take the grocery panniers off when they're loaded with the week's worth of groceries. The bike plus 50-60 pounds of vittles is too much for me to heft up the stairs in one go. Oh, woe is me!
Come to think of it, I also have to lift the bike up a couple of steps to get it inside at work, and of course, at both locations, my bikes hang on the wall by their front wheels for storage, which also requires lifiting. I manage this too without being either strapping or young.