Originally Posted by
phoebeisis
Wow- can you still ride with a 20% EF ?
You sorta lucked out-very very few MDs would be brave enough to prescribe testosterone for someone who must/might have CAD.
Especially now-after some recent study(not a great study since patients were probably given large doses)-indicating increased MI risk with testosterone supplementation
You certainly benefit from it-
and it is faintly possible that it has some cardiac protective effect at " low normal" levels -and the "bad cardiac effects" are at much higher levels.
HRT in women- became Verboten after the BIG STUDY(2001 early release and ended early)- 1,000,000 women study or whatever it was called.
It showed increased risk breast cancer and INCREASED CAD risk- the CAD was the opposite of what was expected-breat cancer risk-not a surprise-good effect on bones was demonstrated and some odd protective effects-bowel cancer decreased risk etc
In any case-ALMOST ALL WOMEN were IMMEDIATELY rapidly tapered off HRT- and far far fewer were started on it
fast forward to 2012 or so- followup results of a DANISH STUDY- good study-released(study actually had be stopped early because of 1,000,000 study) anyway followup demonstrated a PROTECTIVE CARDIAC EFFECT- along with good for bones other cancers-BAD BREAST cancer effect was still present I think.
OPPOSITE CARDIAC result from 1000000 woman study-exact opposite
Well the HRT studies-were different-different drugs-different way of dosing-
BUT MOST IMPORTANTLY the Danes gave it to perimenopausal women-50,51 yo
We gave it to 61,62 yo women-who hadn't had "much" in the way of hormones in 10-11 years
so we SUDDENLY dumped high levels of estrogens/progestins- on women who were more or less naive to them
and we got the BAD cad -but not surprising- result
Now the Danish study hasn't changed current therapy in the USA- HRT is still frowned on-mainly for breast cancer risk-but MI risk is still-incorrectly-touted as a reason to "not start HRT"
HRT also makes women "feel better look younger" middle aged women-their skin and muscle tone-suddenly aged about 5 years after HRT became "bad"
it is POSSIBLE-big maybe- that HRT women and men-is "better" when not passed thru GI track-meaning making a 1st pass thru liver
Oh well-I have run on-you lucked out-brave MD-amazing what hormones can do-same EF but much better work tolerance
Can you still ride (wife had MI- baddish one-LAD etc)-she still manages occasional brief ballet type workouts-she has vasculitis-so her problems are ongoing-since 2005
Can you ride a little?
You do realize that most Female HRT uses Horse estrogen as it degrades slower and was patent able.
Analagous to using anabolic steroids as seen in Bodybuilding, Pro sports and etc. such as Trenbolone, or Nadrolone.
When studies are done using actual estogen and progesterone (both are necessary and best protocols vary the ratios) breast cancer is reduced. But those are not patent able and hence will not get expensive studies done in US.