The first doctor I went to favored injections. After a year of that I went to a second doctor that said that bi-weekly injections was insanity and put me on the compounded cream that I use to this day. I never really acheived all those glowing superlatives that were supposed to be results of T replacement therapy. On my own I decided to test E2. I was 12 on a test where 2 is high. That was mostly from injections since I hadn't been on the cream that long by this. Aromatization occurs in the liver. It doens't matter whether you inject of apply cream, the first pass throught the liver is going to happen. You cannot prevent it. Some men can take a lot of T and not have it all turn to E. I take only a little T and my E goes way up. I use Arimidex to lower E2. They are so powerful and work so fast that I was too low before I knew it and was just making things worse by taking 1/2 pills EOD. Eventually I tested E2 again and discovered this. To say that doctors are mostly clueless about this stuff is an understatement. Google is your lifeline. My doctor really functions as a legal front door through which I can acquire the therapies I need. I drive the research and direction of the ongoing adventure that is finding an optimum level of vitality and vigor in later mid-life.

H