Everybody makes that dreaded call. As if you dont already hurt bad enough as it is, then comes the adding of personal insult to injury. It happens. It is commendable to ride to the edge of your limits in this activity. But it just doesnt feel good to quit. For me, barring a crash/injury....it's the only thing worse than walking up a hill.
ETA: But I gotta add, getting up for some "hair of the dog" and riding 24mi the next morning...man, that's sprouting a pair!!