Kind of depends on what patches you are using.
If you have a cheap patch kit that's akin to pasting bricks to the tube, you probably will have bad luck.
If you have something like REMA patches, (I see 10 Wheels posted a pic of REMA in post number 4) with a feathered edge, your chances of success are MUCH better.
I'd get a new tube and try patching the old. IF it works, you have a spare tube ready for emergency.