Dammit guys... I need some advice...

Going to pick up my first road bike. Want something that I can use for the next several years; so not entry, but not top of the line. Want to be able to upgrade components and not really worry about the frame. I've narrowed it down to two bikes... 2014 Felt F4 or a 2012 (new, never owned) Look 586 (or 2013 if I can find one). Love them both and would be happy with either. When I'm looking to upgrade, should I place Di2 at the top or bottom of the upgrade list? I ask because the Look doesn't have internal cable routing whereas the Felt does. Suggestions********************