i ride a lot and tour some and have 26, 650c, 700c, and 27" wheels. all other things being equal, IME, the bigger the better.

and believe it or not, when after a series of poor choices and bad luck, i ended up with no tube or tire in a little dump of a town far from anywhere, with a "hardware store" that looked more like my late great uncle's garage, i found only shrader valved tubes, and one ancient 27" tire.