I'm on statins now and my cardio meds have dramatically lowered my max hr. Now I'm back to where 140 is right about my tipping point for moving into anaerobic time. 157 is pretty close to the highest number I can get to but I'll know more after a stress test in a week or so....but they have me off the hr lowering statin the morning of the test so I can raise my HR in a "normal" fashion. I have to remember to ask my cardiologist if I can't just skip my magic pill the morning of a race...