Thanks for all the replies. I will definitely check out the Secteur. Specialized was the first brand I rode and raced on, so I have always had a soft spot for them.

The larger tires have helped with general comfort, but that really isn't the problem. I don't exactly feel "beat up", my Orbea handles the road buzz and bumps fairly well. The pain is more from staying in the same position for a long period of time.

I have tried quite a few stems with different lengths and different angles, and that has helped a lot with the shoulder issues and taking weight off my hands (No spacers, though). The problem is that I have not been able to find a stem combo yet that puts me upright enough with my saddle position. When I start to move the saddle around from it's current position, my bad knee starts to act up. So, I basically have to choose between knee pain or back pain.

I also appreciate the advice on some of the other brands and swapping parts vs. selling. One question I do have is roughly what do y'all think the Orbea is worth? Fstshnk said $700, is that about right, or should I go higher or lower? Like I said, I am a little out of touch on current pricing trends. Thanks again for all the input!