There's a inland route called the Pacific Crest Bicycle Trial. It's absolutely beautiful, but has an extreme amount of elevation gain.

I've ridden most of Hwy 101 through Oregon in the "wrong" direction and have to say the headwind is hit and miss. It's not always bad. Usually the mornings are okay, but the evenings can be horrendous. Still, I don't think I'd chose to ride from all the way from Berkeley to Seattle north along the coast.

The Willamette Valley has a route called the Willamette Valley Scenic Bikeway - it could be part of a "bail-out" plan if the headwind became too annoying. Consider planing your own route.