I vote for Look pedals also. My foot isn't as large as yours (US 11-1/2, EU 45).
I started out riding clipless using SPD (M-535) and switched to Looks about a year later.
I like the larger platform and with your large foot you should get a pedal with a good sized platform.
You might want to look at mountain bike pedals too. Maybe someone makes one with a large platform. There's no rule that says you can't use mountain bike pedals on a road bike. Get what works best for you.
__________________
The Lord is merciful and gracious, slow to anger and abounding in steadfast love. - Psalm 103:8
I am a cyclist. I am not the fastest or the fittest. But I will get to where I'm going with a smile on my face.