My Novara Strada currently has 35's and room to spare for bigger... eyelets... 105.... it's a versatile frame that I'm excited to take interesting places. Where I live, if you can ride the logging roads,,,, my lord.... you could have some amazing, carless rides into some great terrain. A riding buddy and I keep bringing this possibility up. He on his MTB, me on a road frame with drops and 35's... I'm all in! My days of any kind of technical single-track are long gone; but riding logging roads is a far cry from that.