The Topeak Road Morph didn't review too highly at Outdoor Gear Lab, which has good quality reputable reviews. They cited cons as "Bulky and heavy. Hard to get a good seal. Inaccurate gauge", though noted the benefit of the footpad design :
Topeak Road Morph Review - OutdoorGearLab
They picked the Lezyne Pressure Drive as Editor's Choice. Small or Medium? I'd think Medium for the great volume for larger tubes:
Lezyne Pressure Drive - Mike's Bikes - Road and Mountain Bike Shop, components, parts, accessories, service and repair
Would you suggest the Lezyne Pressure Drive CFH with CO2, or to use a separate stand-alone CO2 inflator?