I started with them at age 59 on my road bike, and rapidly got used to them - maybe 2-3 days. However, I had worn loose toe clips on a mountain bike for a few months prior. I alternate between a bike with pedals only, one with loose toe clips, and one with clipless with no problem at all. I can unclip at any point in the rotation, but it is easiest at 6 o'clock - I use Shimano mtn type SPD's. YMMV