My wife is great, she is very supportive of my full-time bike commuting, but she does have some concerns. One time near the beginning I didn't call home before I left work, and when I got home she was crazy because she couldn't reach me at work, and didn't know if I was on the road, or stuck or crashed or injured. So now I tag up before every time I leave work, and she likes that.

Also, I try to share with her information about what I do on my rides to keep safe. Like when we drive by one of my problem intersections, I'll point out "sometimes I'll just get through the intersection and wait at the curb for the light to turn red to hold back the cars so I can change lanes here", or "here is a place where cars have to cross over the bike lane into the right turn lane, so I'm always looking for gaps in the traffic to make sure I can move through, or take extra care to communicate with drivers and watch them close anyways" etc.

Also a good idea as mentioned above to take her on a ride sometime. Preferably a weekend morning when traffic is light...