Closest thing I can think of at the moment is the combination of the Lehigh Gorge Trail and the section of the D&L between White Haven and Glen Summit. Haven't ridden the latter, but the former is about 25 miles from White Haven to the center of Jim Thorpe, where there is at least one B&B. There are also places to eat. Don't think you would have to worry about parking your car on the street in Glen Summit. Or you could park in the municipal lot in Jim Thorpe, ride the trails north to Glen Summit and then do a little road riding to Mountain Top, where there are motels and places to eat.

You might have to make compromises. 50-60 miles is long for a rail-trail in this part of the world.