I don't have any documented evidence but I do know that changing my saddle recently has caused some burning when urinating after riding. I think there is defintely a connection. Since making adjustments to the saddle angle the problem has been solved but I was surprised how that could have caused problems so quickly.

BTW- Up until recently my go to bike was a Nishki Prestige.At least the frame still is as the bike has gone through many upgrades since 1984 when itwas first purchased.

Hope your friend is doing better and gets well quickly.

Oldroadog-