I use Brooks B-17 on all my commuter bikes and a WTB Pure V on my MTB.

Clothing makes a huge difference on some saddles, I wear compression shorts from WalMart and use Chap-Guard Plus udder cream on my private parts. Udder Cream is inexpensive and I buy it at a Tack store, $20.00 for 5 lbs and lasts a long time.
It is also good to clear up existing saddle sores if you have them, just keep your privates very clean and I hand wash my compression shorts after every ride.

I really don't need any protection when I ride my Brooks B-17 saddle though, but still use the compression shorts and UC if I am going on long rides just to be safe, nothing worse than having a sore a$$...lol