Originally Posted by Wooden Tiger

I don't believe the chamois cream is going to help in my case, as it's a matter of a seam being right down the center of the shorts (on the inside of the shorts). While the seam is a flat seam, it is rough. Nonetheless, for lack of a better term, it just "rubs things the wrong way" and irritates quickly. I thought I was going to have to walk my bike back home.

As for debunking a myth, absolutely not. Different strokes for different folks. Things would probably be far more comfortable if there was not a rough seam running down the center of the interior of my cycling shorts. Unfortunately, it's like that on all of them, and I have a few different types of shorts.

Any suggestions on some styles and/or brands to try that aren't designed this way?