My experience: my 2011 Felt Z6 came with Microshifters as the stock shifters.

They were Loud! I called them my shotgun shifters; great for alerting others on the trail :-)

But, they caused me a lot of pain in my right middle finger, which was finger it felt most natural to use. I had to consciously (it wasn't too hard, pain will do that) force myself to use my index finger to shift.

I replaced them w/105s from Shimano and haven't looked back.