In case anyone searches for this thread, I can confirm that only one 57 cm road bike will just barely fit inside the trunk of a 2006 Lexus IS 350 with the wheels removed. It's a tight squeeze. There's no way a second bike will fit in there.
I can also confirm that Lexis is spelled with a U, not an I.
Erm...I can also confirm that a Lexus IS 350 is a damn fine car, very much capable of pinning you to the back of your seat.