Also, Caad 8/10 is a more race inspired geometry as well as the Supersix. The Domane is an endurance geometry which will be more more comfortable for longer rides. The Caads and Supersix are more comparable to the Madone/Emonda in the Trek line. Try them and see what fits you best. I would really suggest seeing if any dealers have a 2013 model left in your size, you save huge and typically only different color schemes.