Originally Posted by
DeadGrandpa
I'm sure there are all kinds of arguments against aspirin these days. I simply don't believe them. Until recently, I am given to understand that something called coumadin was commonly prescribed as a blood thinner. The active ingredient in this is the same ingredient as in rat poison, and I have a philosophical objection to ingesting poison when a non-poisonous substance (aspirin) is readily available and does much the same thing.
Aspirin's LD50 (lethal dose for 50% of the test subjects) for oral administration to rats is about 200 mg/kg. 500 grams (about a pound) is a big rat, so one 325mg aspirin tablet is more than enough to kill two large rats.
Toxicity for both Warfarin (Coumadin) and aspirin is dose dependent for rats and humans. Both can be beneficial in the right dose or lethal in an overdose.