+1
Supple Tires, Supple Rider.

My weight tends to fluctuate between 215 and 230 lbs.
I keep my 25mm tires @ 120 psi rear and 95 psi front on the Sporty Quick bike, as I often carry 10 to 15 lbs. of 'gear' in the Topeak rack trunk w/ the fold out panniers on my 30+ mi. r/t commute, often stopping for groceries on the way home.
My experience has been that the softer front tire improves comfort (mutes 'road buzz') and handling (improves traction), while the higher pressure of the rear tire eliminates pinch flats (tough to 'hop' rear tire when loaded w/ 20-30 lbs. of vittles in the panniers).
I learned long ago to 'Ride Light' (unweighting saddle, using legs as active suspension) even when I was much heavier than I am now.