Joined: Jan 2009
Posts: 44,231
Likes: 6,489
From: New York, NY, and High Falls, NY, USA
Bikes: 1962 Rudge Sports, 1971 Raleigh Super Course, 1971 Raleigh Pro Track, 1974 Raleigh International, 1975 Viscount Fixie, 1982 McLean, 1996 Lemond (Ti), 2002 Burley Zydeco tandem
If it is the classic problem of the chain skipping over the teeth, no, there is no adjustment you can make to mitigate the problem. You can avoid the gears that skip, though.
When you get a new chain, be sure to lubricated it frequently enough to prevent this. Replace it before it is terribly worn. Doing so will prevent (or slow) the wear of the cogs. Your freewheel/cassette can last several chains if you take care of your chains.