I don't think the OP has to ask, or that we have to warn about any danger. The wall is separated from the bead for some distance, and I doubt the tire will hold full inflation pressure long enough to be ridden.
This is unrepairable damage, possibly from riding when flat or severely underinflated, or possibly from the edge or worn overhang from a worn brake shoe slowly cutting through there.
Whenever I see this kind of damage, I immediately remove the wheel and look/feel for overhang on the upper (outer to rim) shoe. If I see any, I file it off with a rasp, then reinstall the shoe lower to prevent a repeat event.
Otherwise, if nothing is found, get out the butter and jam because the tire is toast.
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