I might suggest that the fit geometry is designed first, then the frame geometry with an eye to the components that will make the fit work. Good bike design is a back and forth process but the fit should establish as much as possible.

In an ideal world there would be a range of wheel, crank, bar, stem, levers sizes with equal quality and performance. But that's not the case so compromise is a part of real world design. Where we call the threshold of acceptable compromise is different for each of us as well as every builder/manufacturer. Andy.