I'm 275 and ride on 700x28.

Vittoria Zafiro wire at 120-130 PSI

Front: anywhere between 600 and 1000 miles looking almost like brand new, and another 400-600 before the middle starting to look squarish...

Rear: cut the the above numbers in half.

I bet these tires can do another few hundred miles before it will be unsafe, but I like my tires looking new and fresh.

Vittoria Rubino wire at 110-120 PSI

Front: Up to 1000 miles without visible wear, and another 500-600 miles before the middle stripe is at the level with the rest of the tire tread. I can easily, and safely push this on for another few hundred miles...

Rear: Cut the above numbers in half

I ride everywhere...city streets, crushed limestone trails, packed and rocky country roads. Very good all around tire.
The only issue I have with them are sidewalls. Both Zaffiro and Rubino will develop cracks sooner than later. It's not a huge issue, but quality of the rubber should be better. I don't complain too much, since they are very cheap, and gives me awesome service and flat protection...or maybe I'm just lucky lol

Btw...the worst tires I used - Specialized armadillos...Bunch of cuts and flats for a premium price...