As to the nose up thing, I'm wondering if that doesn't work better for those that sit more upright rather than those who ride in the drops or ride more stretched out.

I do think that Brooks saddles are more finicky in regard to positioning than most other saddles, in that only a small difference in tilt or set back can make a huge difference in comfort. Once I find that sweet spot, I HATE to move my saddle or seatpost.