Used to commute along the Erie Canal, well quite a long time ago. Back when laptops were rather heavy, I had to lug it back and forth. The route was rather bumpy and laptops at the time didn't take shock very well.

I found a marvelous armored backpacks with a suspension of sorts. Clothes and such were in a trunk.

I would suggest that you consider ways to reduce shock or impact. Larger softer tires will go a long ways, basic armored laptop bag will also help.

Oh, they really don't like water either.