I am a 210+ lb rider who still has the Palo Alto alloy rollers that I bought as a 13 year old in 1981!

What the peeps above said: new, known-good tires and tubes. 120lbs pressure. These should give you proper rolling resistance.

Examine your riding space, and look for anything within about a seven foot area that could injure you if you fell laterally onto it. Tables, fragile things, pets all should be kept ten feet away from you. You can and may come off the rollers at 30 mph. Even though your wheels won't have enough inertia to take you anywhere if they suddenly hit the stationary ground, you could find yourself falling over while clipped in. Falling through a glass table while trying to get your footing could suck.

I like to put a towel on the ground to catch sweat and liquids. A small fan up front for air flow. You will get hotter than you imagine. I like to play cycling videos on a computer or TV in front of me, or listen to radio that will motivate or keep your mind busy. Roller riding can induce boredom, unlike riding on the actual road. Play games for practicing spinning smoothness, speed, shifting, etc. I used to juggle while i rode, but I was a crazy kid.