I do point-to-point. When I have gone coast-to-coast, I flew to the start point each time, and then flew back from the end point. When I did it with a single touring bike, I was able to take my bike with me each way as onboard baggage. When I did it with a tandem, my local bike shop shipped the tandem (and BOB trailer) to an accommodating bike shop at the start point, and then a similar bike shop at the trip's destination shipped it back to me local bike shop at the end.

On several other tours, I/we started at home, and then brought the bikes back from the destination on vehicles. On one ride, a family member carried the two bikes on a vehicle to the start point, and then met us at the destination several days later to carry the bikes back home.