personally, i would prefer a bike that can run both 406 and 451 wheelsets.
that would mean Hub, disc or drum, brakes .. or a frame with say Rim Brakes for the 451, and disc brakes for the 406.
the BD minivelo doesn't come that way , but, a Bike Friday could be BTO with those features.
What wheelset are those ? Can they be fitted with 10 speed cassette?
note its a 1 speed freewheel , I doubt it but if you have a Machine Shop you can modify things .