I have been hearing about the issues of interference from spoke crosses for decades. I have also been lacing 36 hole wheels 4X for as long, even Campy Tipo high flanges. (I have many thousands of miles of 4X 36 hole Tipo hubs, maybe 65,000.) Spoke head breakage has been completely normal (and in recent years a lot less than breakages at the threads). I might have 5 spoke breakages of all types over the lifespan of a pair of wheels that each get three rims that see road grit and rebuilds using the same spokes. Now I am 150 pounds and a cliimber, not a powerhouse in any way. Still, I think the issue of the spokes interfering is overblown. So early in life, they take a set due to the interference. Kinda like early in life the elbow bend is slightly altered by the hub drilling. Is that a problem? Doesn't seem to be for the elbows.

Ben