I've been as high as 245 and as low as 211 and I think I have about 8,000 miles on some of the components (shifters, brakes). I've replaced the crank twice and both derailleurs but not for performance reasons. Went from a standard to a compact to a power meter crank, and the FD needed swapping when I got a braze on frame, and I got the wifli RD to tackle some particularly ornery hills near me. I still have the older parts - they're perfectly functional.
One thing I'd steer clear of is the supposed top of the line BB - ceramic bearings in a BB are a complete waste of time, and SRAM says you need to clean them every couple hundred miles. Um, no thanks.