Pine Bark? look a lot of this health food stuff is unproven, they have no long term data on health effects taking that stuff, but short term there are issues, see: Error 500 activeingredientid=1019&activeingredientname=pycnogenol And this: Adverse Effects of Pine Bark Extract | LIVESTRONG.COM

Along with those side effects is irritability and fatigue. In addition there is no standardized and the amount of concentration is difficult to determine how much should be taken.

I've never been a proponent of most of the stuff sold in health food stores, this is multi billion dollar industry with no oversight. Most people who go to these places buy mega vitamins and are simply flushing about 99% of down the toilet unused, so you're essentially flushing money down the toilet. In addition to that is the issue of toxicity levels are routinely reached not only with vitamins but herbs too, with usually no short term effects but over the long term may be causing illnesses. I know that I had 2 friends who were very much into this stuff along with vegan diet and plenty of exercise, one was registered in various aspects of this stuff, both died of cancer before they were 50. Was this related to long term toxic levels of vitamins and herbs? I don't know and there is no way to tell, maybe if, big if, someone did a thorough autopsy that could have been determined.

If you eat right you're body gets all it needs from food, even doctors will tell you the most you should need is very cheap and generic daily vitamin, I don't take anything. Some elderly people have problems with extreme fatigue and vitamin B12 shots but even that has been controversial, but supposedly if the doctor does a blood test and finds the person deficient then a B12 shot may be beneficial. Keep in mind that a shot is absorbed better into the body then a pill, and b12 doesn't build up a toxicity level like some other vitamins, so in that vein (no pun intended) a B12 shot may not do anything but it won't hurt you either.