I used to use a Pika Packworks and now use a Orucase (AKA Bike Ninja). Just used the Orucase last week when I flew to Denver and back.

I have yet to have anything bad happen to my bikes yet but that is always a worry with any soft sided case. The advantage though is that roughly 50% of the time I have flown with the Pika I have avoided fees and so far the Orucase has a 100% 'avoidance of fees' average (But that is only one "trip", although it was me and the SO which equates to seeing 4 "trips" with zero fees). The airline people seem to pick up that they are bikes (despite my answering the question as to the contents with "Trade show display"). But it seems like the smaller and lighter the bags are the more likely they are to decide that gouging you for 150$-200$ is a dick move.