I recently purchased a Mavic Open Pro rim with Ultegra cassette hub. Installed on my steel frame, the center of the wheel is offset about 1/8" further to the R/S of center (brake center bolt). I would think that it should be centered in the frame. One thing I'm noticing, is that when the chain is on the large chainwheel and smallest sprocket, it rubs against the outboard front derailer guide. Should I readjust the axle and relocate shims to bring he wheel into center alignment with the frame? This might eliminate the chain rub while centering the wheel. There seems to be mush more space on the L/S of the hub than on the R/S, leading me to think that the hub is too far to the right. I've checked the frame alignment with string (as per Sheldon Brown) and the frame seems to be OK.
Thanks,
Rich