I don't know what your base of information is so I will start from zero. First, go get a fitting. From that you may find that there are plenty of frames that will fit you precluding the need for a custom frame. Assuming that you can buy off the shelf, it's then a matter of frame material and aesthetics. Lots of choices from Nashbar to Colnago. If you can do the work yourself it's just a matter of getting killer deals on the components you want. Or not, depending on how much money you want to throw at it. Custom builders like Gunnar, Zen, Independent Fabrication, Guru, et. al. can build you a custom frame and outfit it for you. You have lots of choices.

Next June I will turn 70 and I'm going through this mental process too. Kind of wanting to give myself a birthday present of a new bike. Sometimes the mental process can make me crazy so I'm trying to go slow and chill out right now.