Originally Posted by
elcruxio
Doesn't matter with spokes. A spoke goes through it's individual stress cycles and is not really affected by the other spokes. You can mix and match as much as you like.
I don't think that is completely true. I think it is likely that the 4 different type spokes (drive and non drive side inners and outers) in a rear wheel all interact with the other three neighboring types. I don't think mismatching is sudden death or anything but do think that matching is better than not matching when it comes to gauge and type of butting.
That said it isn't a big enough deal that I actually worry about it enough to go back and replace any mismatched ones.