Originally Posted by
gaucho777
^You're welcome. First thing I'd do is to hold the end of one of your crank arms with your fingertips while off the bike and try to move it side to side. There should be no side to side movement. (Adjusting the bottom bracket is a fine balance between tight enough to get rid of any lateral movement, and not too tight that the bearings are getting squeezed. Usually requires special tools.)
If that's not the cause of the problem, you may want to check this out:
Bicycle Bike Noises, Clicks, Ticks, Creaks, Clunks, Knocks Repair by Jim Langley
That, and do the same with each pedal.